RYR2 Antikörper (AA 901-1192)

Produktnummer ABIN7168509

Produktdetails anti-RYR2 Antikörper

Target: RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

Bindungsspezifität: AA 901-1192

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RYR2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ryanodine receptor 2 protein (901-1192AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RYR2

Target: RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

Andere Bezeichnung: RYR2 (RYR2 Produkte)

Synonyme: RYR2 antikoerper, ARVC2 antikoerper, ARVD2 antikoerper, RYR-2 antikoerper, RyR antikoerper, VTSIP antikoerper, 9330127I20Rik antikoerper, ryanodine receptor 2 antikoerper, ryanodine receptor 2, cardiac antikoerper, RYR2 antikoerper, Ryr2 antikoerper

Hintergrund:

Background: Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.

Aliases: ARVC2 antibody, ARVD2 antibody, Cardiac muscle ryanodine receptor antibody, Cardiac muscle ryanodine receptor-calcium release channel antibody, hRYR-2 antibody, ryanodine receptor 2 (cardiac) antibody, Ryanodine receptor 2 antibody, RyR antibody, RYR-2 antibody, RyR2 antibody, RYR2_HUMAN antibody, Type 2 ryanodine receptor antibody, VTSIP antibody

UniProt: Q92736

Pathways: Myometrial Relaxation and Contraction