SENP1 Antikörper (AA 63-214)

Produktnummer ABIN7168833

Produktdetails anti-SENP1 Antikörper

Target: SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))

Bindungsspezifität: AA 63-214

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SENP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Sentrin-specific protease 1 protein (63-214AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SENP1

Target: SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))

Andere Bezeichnung: SENP1 (SENP1 Produkte)

Synonyme: SuPr-2 antikoerper, 2310046A20Rik antikoerper, D15Ertd528e antikoerper, E330036L07Rik antikoerper, suPr-2 antikoerper, senp1 antikoerper, senp1a antikoerper, xsenp1 antikoerper, SENP1 antikoerper, Senp1 antikoerper, senp1b antikoerper, SUMO1/sentrin specific peptidase 1 antikoerper, SUMO1/sentrin specific peptidase 1 S homeolog antikoerper, sentrin/SUMO-specific protease 1 antikoerper, SUMO1/sentrin specific peptidase 1 L homeolog antikoerper, SENP1 antikoerper, Senp1 antikoerper, senp1.S antikoerper, senp1.L antikoerper, senp1 antikoerper

Hintergrund:

Background: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjugates SUMO2 from MTA1. Desumoylates CCAR2 which decreases its interaction with SIRT1 (PubMed:25406032).

Aliases: SENP 1 antibody, SENP1 antibody, SENP1_HUMAN antibody, Sentrin specific protease 1 antibody, Sentrin-specific protease 1 antibody, Sentrin/SUMO specific protease 1 antibody, Sentrin/SUMO specific protease antibody, Sentrin/SUMO specific protease SENP 1 antibody, Sentrin/SUMO specific protease SENP1 antibody, Sentrin/SUMO-specific protease SENP1 antibody, SUMO1/sentrin specific peptidase 1 antibody, SUMO1/sentrin specific protease 1 antibody, SuPr 2 antibody, SuPr2 antibody

UniProt: Q9P0U3

Pathways: Positive Regulation of Endopeptidase Activity