SENP6 Antikörper (AA 1-270) (FITC)
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- Target Alle SENP6 Antikörper anzeigen
- SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))
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Bindungsspezifität
- AA 1-270
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SENP6 Antikörper ist konjugiert mit FITC
- Applikation
- Bitte anfragen
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Sentrin-specific protease 6 protein (1-270AA)
- Isotyp
- IgG
- Top Product
- Discover our top product SENP6 Primärantikörper
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))
- Andere Bezeichnung
- SENP6 (SENP6 Produkte)
- Synonyme
- SSP1 antikoerper, SUSP1 antikoerper, 2810017C20Rik antikoerper, E130319N12Rik antikoerper, Susp1 antikoerper, mKIAA0797 antikoerper, fc83h02 antikoerper, im:7148342 antikoerper, wu:fc83h02 antikoerper, zgc:171230 antikoerper, SUMO1/sentrin specific peptidase 6 antikoerper, SUMO/sentrin specific peptidase 6 antikoerper, SUMO1/sentrin specific peptidase 6a antikoerper, SENP6 antikoerper, Senp6 antikoerper, senp6a antikoerper
- Hintergrund
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Background: Protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. Processes preferentially poly-SUMO2 and poly-SUMO3 chains, but does not efficiently process SUMO1, SUMO2 and SUMO3 precursors. Deconjugates SUMO1 from RXRA, leading to transcriptional activation. Involved in chromosome alignment and spindle assembly, by regulating the kinetochore CENPH-CENPI-CENPK complex. Desumoylates PML and CENPI, protecting them from degradation by the ubiquitin ligase RNF4, which targets polysumoylated proteins for proteasomal degradation. Desumoylates also RPA1, thus preventing recruitment of RAD51 to the DNA damage foci to initiate DNA repair through homologous recombination.
Aliases: 2810017C20Rik antibody, FLJ11355 antibody, FLJ11887 antibody, KIAA0389 antibody, KIAA0797 antibody, SENP 6 antibody, Senp6 antibody, SENP6_HUMAN antibody, Sentrin specific protease 6 antibody, Sentrin-specific protease 6 antibody, Sentrin/SUMO specific protease SENP6 antibody, Sentrin/SUMO-specific protease SENP6 antibody, SSP 1 antibody, SSP1 antibody, SUMO 1 specific protease 1 antibody, SUMO 1 specific protease antibody, SUMO-1-specific protease 1 antibody, SUMO1 specific protease 1 antibody, SUMO1 specific protease antibody, SUMO1/sentrin specific peptidase 6 antibody, SUSP 1 antibody, SUSP1 antibody
- UniProt
- Q9GZR1
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