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PAK3 Antikörper (AA 70-190) (Biotin)

PAK3 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal Biotin

Produktnummer ABIN7169129

Datenblatt (PDF)

Target Alle PAK3 Antikörper anzeigen

PAK3
Bindungsspezifität
16

8

8

5

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1
AA 70-190
Reaktivität
59

22

11

2
Human
Wirt
54

5

2
Kaninchen
Passende Sekundärantikörper
Klonalität
55

7
Polyklonal
Konjugat
35

5

4

3

2

2

1

1

1

1

1

1

1

1

1

1

1
Dieser PAK3 Antikörper ist konjugiert mit Biotin
Applikation
57

35

27

13

13

7

5

3

1

1
ELISA

Kreuzreaktivität

Human

Aufreinigung

>95%, Protein G purified

Immunogen

Recombinant Human Serine/threonine-protein kinase PAK 3 protein (70-190AA)

Isotyp

IgG

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anti-PAK3 (PAK3) (AA 124-152) antibody
PAK3 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-PAK3 (PAK3) (AA 70-190) antibody
PAK3 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-PAK3 (PAK3) (AA 124-152), (N-Term) antibody
PAK3 Reaktivität: Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB34657 unconjugated

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PAK3 Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated

anti-PAK3 (PAK3) (Ser154) antibody
PAK3 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-PAK3 (PAK3) (AA 218-247) antibody
PAK3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB1223-1224 unconjugated

anti-PAK3 (PAK3) (AA 1-100) antibody
PAK3 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

anti-PAK3 (PAK3) (AA 218-247) antibody
PAK3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C,-80 °C

Informationen zur Lagerung

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target

PAK3

Andere Bezeichnung

PAK3 (PAK3 Produkte)

Hintergrund

Background: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments. May also be involved in early neuronal development.
Aliases: PAK3 antibody, OPHN3 antibody, Serine/threonine-protein kinase PAK 3 antibody, EC 2.7.11.1 antibody, Beta-PAK antibody, Oligophrenin-3 antibody, p21-activated kinase 3 antibody, PAK-3 antibody

UniProt

O75914