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PIM3 Antikörper (AA 278-326)

PIM3 Reaktivität: Human ELISA, WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7169149
  • Target Alle PIM3 Antikörper anzeigen
    PIM3 (Pim-3 Oncogene (PIM3))
    Bindungsspezifität
    • 9
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 278-326
    Reaktivität
    • 27
    • 12
    • 2
    Human
    Wirt
    • 25
    • 2
    Kaninchen
    Klonalität
    • 25
    • 2
    Polyklonal
    Konjugat
    • 11
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PIM3 Antikörper ist unkonjugiert
    Applikation
    • 15
    • 14
    • 12
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Serine/threonine-protein kinase pim-3 protein (278-326AA)
    Isotyp
    IgG
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    PIM3 (Pim-3 Oncogene (PIM3))
    Andere Bezeichnung
    PIM3 (PIM3 Produkte)
    Synonyme
    pim1-a antikoerper, pim-3 antikoerper, BC026639 antikoerper, Kid1 antikoerper, Serine/threonine-protein kinase Pim-3 antikoerper, Pim-3 proto-oncogene, serine/threonine kinase S homeolog antikoerper, Pim-3 proto-oncogene, serine/threonine kinase antikoerper, pim-3 oncogene antikoerper, proviral integration site 3 antikoerper, pim3 antikoerper, pim3.S antikoerper, PIM3 antikoerper, Pim3 antikoerper
    Hintergrund

    Background: Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.

    Aliases: Kid 1 antibody, Kid1 antibody, Kinase induced by depolarization antibody, ONCOGENE PIM3 antibody, PIM 3 antibody, Pim 3 oncogene antibody, Pim-3 proto-oncogene, serine/threonine kinase antibody, PIM3 antibody, Pim3 oncogene antibody, PIM3_HUMAN antibody, Protein kinase Kid 1 antibody, Protein kinase Kid1 antibody, Serine/threonine kinase Pim 3 antibody, Serine/threonine kinase Pim3 antibody, Serine/threonine protein kinase Pim 3 antibody, Serine/threonine protein kinase Pim3 antibody, Serine/threonine-protein kinase Pim-3 antibody

    UniProt
    Q86V86
    Pathways
    Negative Regulation of Hormone Secretion
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