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ULK3 Antikörper (AA 44-240)

ULK3 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7169213
  • Target Alle ULK3 Antikörper anzeigen
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    Bindungsspezifität
    • 14
    • 11
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 44-240
    Reaktivität
    • 54
    • 46
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 61
    • 7
    • 2
    Kaninchen
    Klonalität
    • 64
    • 6
    Polyklonal
    Konjugat
    • 31
    • 6
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ULK3 Antikörper ist unkonjugiert
    Applikation
    • 62
    • 39
    • 10
    • 10
    • 9
    • 6
    • 3
    • 1
    ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Serine/threonine-protein kinase ULK3 protein (44-240AA)
    Isotyp
    IgG
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  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    Andere Bezeichnung
    ULK3 (ULK3 Produkte)
    Synonyme
    zgc:162196 antikoerper, 1200015E14Rik antikoerper, unc-51 like kinase 3 antikoerper, unc-51 like kinase 3 L homeolog antikoerper, unc-51-like kinase 3 antikoerper, ULK3 antikoerper, ulk3 antikoerper, Ulk3 antikoerper, ulk3.L antikoerper
    Hintergrund

    Background: Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.

    Aliases: DKFZP434C131 antibody, FLJ90566 antibody, Serine/threonine-protein kinase ULK3 antibody, Ulk3 antibody, ULK3_HUMAN antibody, unc 51 like kinase 3 (C. elegans) antibody, Unc-51-like kinase 3 antibody

    UniProt
    Q6PHR2
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