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Shugoshin Antikörper (AA 260-439) (Biotin)

SGOL1 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN7169546
  • Target Alle Shugoshin (SGOL1) Antikörper anzeigen
    Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))
    Bindungsspezifität
    • 10
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 260-439
    Reaktivität
    • 44
    • 5
    • 5
    • 1
    • 1
    Human
    Wirt
    • 42
    • 3
    Kaninchen
    Klonalität
    • 43
    • 2
    Polyklonal
    Konjugat
    • 25
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Shugoshin Antikörper ist konjugiert mit Biotin
    Applikation
    • 31
    • 26
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Shugoshin 1 protein (260-439AA)
    Isotyp
    IgG
    Top Product
    Discover our top product SGOL1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Shugoshin (SGOL1) (Shugoshin 1 (SGOL1))
    Andere Bezeichnung
    SGO1 (SGOL1 Produkte)
    Synonyme
    sgo1 antikoerper, NY-BR-85 antikoerper, SGO antikoerper, Sgo1 antikoerper, 3300001M08Rik antikoerper, C81037 antikoerper, shugoshin 1 antikoerper, shugoshin centromeric cohesion 1 antikoerper, shugoshin 1 L homeolog antikoerper, Sgo1 antikoerper, sgo1 antikoerper, sgo1.L antikoerper, SGO1 antikoerper
    Hintergrund

    Background: Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the STAG2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by ESPL1/separase at anaphase. Essential for proper chromosome segregation during mitosis and this function requires interaction with PPP2R1A. Its phosphorylated form is necessary for chromosome congression and for the proper attachment of spindle microtubule to the kinetochore. Necessary for kinetochore localization of PLK1 and CENPF. May play a role in the tension sensing mechanism of the spindle-assembly checkpoint by regulating PLK1 kinetochore affinity. Isoform 3 plays a role in maintaining centriole cohesion involved in controlling spindle pole integrity.

    Aliases: hSgo 1 antibody, hSgo1 antibody, NY BR 85 antibody, Serologically defined breast cancer antigen NY BR 85 antibody, Serologically defined breast cancer antigen NY-BR-85 antibody, SGO 1 antibody, SGO antibody, SGO L1 antibody, SGO1 antibody, SGOL 1 antibody, SGOL1 antibody, SGOL1_HUMAN antibody, Shugoshin 1AB protein antibody, Shugoshin 1CD protein antibody, Shugoshin 1EFprotein antibody, Shugoshin 1GH protein antibody, Shugoshin 1KL protein antibody, Shugoshin like 1 (S. pombe) antibody, Shugoshin like 1 antibody, Shugoshin-like 1 antibody

    UniProt
    Q5FBB7
    Pathways
    Maintenance of Protein Location
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