SIGMAR1 Antikörper (AA 112-169)

Produktnummer ABIN7169599

Produktdetails anti-SIGMAR1 Antikörper

Target: SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Bindungsspezifität: AA 112-169

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIGMAR1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Sigma non-opioid intracellular receptor 1 protein (112-169AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SIGMAR1

Target: SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Andere Bezeichnung: SIGMAR1 (SIGMAR1 Produkte)

Synonyme: ALS16 antikoerper, OPRS1 antikoerper, SIG-1R antikoerper, SR-BP antikoerper, SR-BP1 antikoerper, SRBP antikoerper, sigma1R antikoerper, AL024364 antikoerper, Oprs1 antikoerper, mSigmaR1 antikoerper, Sigma1R antikoerper, oprs1 antikoerper, zgc:56378 antikoerper, sigma non-opioid intracellular receptor 1 antikoerper, sigma non-opioid intracellular receptor 1 L homeolog antikoerper, SIGMAR1 antikoerper, Sigmar1 antikoerper, sigmar1.L antikoerper, sigmar1 antikoerper

Hintergrund:

Background: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration (PubMed:16472803, PubMed:9341151). Necessary for proper mitochondrial axonal transport in motor neurons, in particular the retrograde movement of mitochondria (By similarity).

Aliases: Aging associated gene 8 protein antibody, Aging-associated gene 8 protein antibody, AL024364 antibody, hSigmaR1 antibody, mSigmaR1 antibody, opioid receptor, sigma 1 antibody, opioid receptor, sigma 1 isoform 1 antibody, RP23 167I12.6 antibody, SGMR1_HUMAN antibody, SIG 1R antibody, SIG-1R antibody, Sigma 1-type opioid receptor antibody, Sigma non-opioid intracellular receptor 1 antibody, sigma1 receptor antibody, Sigma1-receptor antibody, Sigma1R antibody, Sigmar1 antibody, SR BP antibody, SR-BP antibody, SR31747 binding protein antibody, SR31747-binding protein antibody, SRBP antibody

UniProt: Q99720

Pathways: SARS-CoV-2 Protein Interaktom