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SMUG1 Antikörper (AA 1-177)

SMUG1 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7169740
  • Target Alle SMUG1 Antikörper anzeigen
    SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1))
    Bindungsspezifität
    • 9
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-177
    Reaktivität
    • 46
    • 18
    • 17
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 40
    • 5
    • 1
    Kaninchen
    Klonalität
    • 44
    • 2
    Polyklonal
    Konjugat
    • 25
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SMUG1 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 23
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Single-strand selective monofunctional uracil DNA glycosylase protein (1-177AA)
    Isotyp
    IgG
    Top Product
    Discover our top product SMUG1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1))
    Andere Bezeichnung
    SMUG1 (SMUG1 Produkte)
    Synonyme
    SMUG1 antikoerper, xsmug1 antikoerper, 1200013B09Rik antikoerper, A930006H09Rik antikoerper, C85220 antikoerper, FDG antikoerper, HMUDG antikoerper, UNG3 antikoerper, single-strand-selective monofunctional uracil-DNA glycosylase 1 antikoerper, single-strand selective monofunctional uracil DNA glycosylase antikoerper, single-strand-selective monofunctional uracil-DNA glycosylase 1 L homeolog antikoerper, SMUG1 antikoerper, smug1 antikoerper, smuG1 antikoerper, smuG antikoerper, LOC5577584 antikoerper, CpipJ_CPIJ002767 antikoerper, Smug1 antikoerper, smug1.L antikoerper
    Hintergrund

    Background: Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases. The activity is damage-specific and salt-dependent. The substrate preference is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at low salt concentration, and dsDNA (G pair) > dsDNA (A pair) > ssDNA at high salt concentration.

    Aliases: FDG antibody, HMUDG antibody, MGC104370 antibody, Single strand selective monofunctional uracil DNA glycosylase 1 antibody, Single strand selective monofunctional uracil DNA glycosylase antibody, Single-strand selective monofunctional uracil DNA glycosylase antibody, SMUG 1 antibody, Smug1 antibody, SMUG1 protein antibody, SMUG1_HUMAN antibody, UNG 3 antibody, UNG3 antibody

    UniProt
    Q53HV7
    Pathways
    DNA Reparatur
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