SLC38A9 Antikörper (AA 1-119) (Biotin)

Produktnummer ABIN7169973

Produktdetails anti-SLC38A9 Antikörper (Biotin)

Target: SLC38A9 (Solute Carrier Family 38, Member 9 (SLC38A9))

Bindungsspezifität: AA 1-119

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC38A9 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Sodium-coupled neutral amino acid transporter 9 protein (1-119AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SLC38A9

Target: SLC38A9 (Solute Carrier Family 38, Member 9 (SLC38A9))

Andere Bezeichnung: SLC38A9 (SLC38A9 Produkte)

Synonyme: MGC81406 antikoerper, 4833412L08Rik antikoerper, 6720411P22Rik antikoerper, 9130023D20Rik antikoerper, 9430067K09Rik antikoerper, A730092C09 antikoerper, RGD1311881 antikoerper, solute carrier family 38 member 9 antikoerper, solute carrier family 38 member 9 L homeolog antikoerper, solute carrier family 38, member 9 antikoerper, SLC38A9 antikoerper, slc38a9.L antikoerper, slc38a9 antikoerper, Slc38a9 antikoerper

Hintergrund:

Background: Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acids. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids (PubMed:25561175, PubMed:25567906). Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids, suggesting that it acts as an amino acid sensor instead (PubMed:25561175, PubMed:25567906). The high concentration of arginine in lysosomes suggests that it acts as an arginine sensor (PubMed:25567906).

Aliases: FLJ46104 antibody, FLJ90709 antibody, Homo sapiens solute carrier family 38, member 9 antibody, MGC120544 antibody, OTTHUMP00000161835 antibody, Putative sodium coupled neutral amino acid transporter 9 antibody, Putative sodium-coupled neutral amino acid transporter 9 antibody, Putative uncharacterized protein FLJ90709 antibody, S38A9_HUMAN antibody, SLC38A9 antibody

UniProt: Q8NBW4