SLC22A1 Antikörper (AA 43-149)
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- Target Alle SLC22A1 Antikörper anzeigen
- SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))
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Bindungsspezifität
- AA 43-149
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SLC22A1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Solute carrier family 22 member 1 protein (43-149AA)
- Isotyp
- IgG
- Top Product
- Discover our top product SLC22A1 Primärantikörper
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SLC22A1 (Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))
- Andere Bezeichnung
- SLC22A1 (SLC22A1 Produkte)
- Synonyme
- SLC22A1 antikoerper, OCT1 antikoerper, HOCT1 antikoerper, oct1_cds antikoerper, Lx1 antikoerper, Oct1 antikoerper, Orct antikoerper, Orct1 antikoerper, Roct1 antikoerper, SLC22A2 antikoerper, solute carrier family 22 member 1 antikoerper, solute carrier family 22 (organic cation transporter), member 1 antikoerper, solute carrier family 22 member 2-like antikoerper, SLC22A1 antikoerper, Slc22a1 antikoerper, LOC421584 antikoerper
- Hintergrund
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Background: Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electrogenic and pH -independent manner. Translocates organic cations across the plasma membrane in both directions. Transports the polyamines spermine and spermidine. Transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. The choline transport is activated by MMTS. Regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase.
Aliases: hOCT1 antibody, OCT1 antibody, oct1_cds antibody, Organic cation transporter 1 antibody, S22A1_HUMAN antibody, Slc22a1 antibody, solute carrier family 22 (organic cation transporter), member 1 antibody, Solute carrier family 22 member 1 antibody
- UniProt
- O15245
- Pathways
- Hormone Transport
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