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SSTR2 Antikörper (AA 304-369)

SSTR2 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7170309
  • Target Alle SSTR2 Antikörper anzeigen
    SSTR2 (Somatostatin Receptor 2 (SSTR2))
    Bindungsspezifität
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 304-369
    Reaktivität
    • 42
    • 25
    • 23
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Human
    Wirt
    • 38
    • 4
    Kaninchen
    Klonalität
    • 37
    • 4
    • 1
    Polyklonal
    Konjugat
    • 31
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SSTR2 Antikörper ist unkonjugiert
    Applikation
    • 19
    • 13
    • 12
    • 8
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Somatostatin receptor type 2 protein (304-369AA)
    Isotyp
    IgG
  • Applikationshinweise
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SSTR2 (Somatostatin Receptor 2 (SSTR2))
    Andere Bezeichnung
    SSTR2 (SSTR2 Produkte)
    Synonyme
    Smstr2 antikoerper, SSTR-2 antikoerper, Smstr-2 antikoerper, sst2 antikoerper, SS2R antikoerper, SSTR2 antikoerper, MGC80373 antikoerper, somatostatin receptor 2 antikoerper, somatostatin receptor 2 L homeolog antikoerper, SSTR2 antikoerper, Sstr2 antikoerper, sstr2.L antikoerper
    Hintergrund

    Background: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

    Aliases: Somatostatin receptor type 2 antibody, SRIF-1 antibody, SRIF1 antibody, SS-2-R antibody, SS2-R antibody, SS2R antibody, SSR2_HUMAN antibody, SST2 antibody, SSTR2 antibody

    UniProt
    P30874
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