SORL1 Antikörper (AA 525-744) (FITC)
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- Target Alle SORL1 Antikörper anzeigen
- SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))
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Bindungsspezifität
- AA 525-744
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SORL1 Antikörper ist konjugiert mit FITC
- Applikation
- Bitte anfragen
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Sortilin-related receptor protein (525-744AA)
- Isotyp
- IgG
- Top Product
- Discover our top product SORL1 Primärantikörper
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))
- Andere Bezeichnung
- SORL1 (SORL1 Produkte)
- Synonyme
- SORL1 antikoerper, C11orf32 antikoerper, LR11 antikoerper, LRP9 antikoerper, SORLA antikoerper, SorLA-1 antikoerper, gp250 antikoerper, SorLA antikoerper, 2900010L19Rik antikoerper, AI596264 antikoerper, AW261561 antikoerper, mSorLA antikoerper, Lr11 antikoerper, RGD619914 antikoerper, sortilin related receptor 1 antikoerper, sortilin-related receptor antikoerper, sortilin-related receptor, L(DLR class) A repeats containing antikoerper, sortilin-related receptor, L(DLR class) A repeats-containing antikoerper, sortilin-related receptor, LDLR class A repeats-containing antikoerper, sorl1 antikoerper, LOC582560 antikoerper, SORL1 antikoerper, Sorl1 antikoerper
- Hintergrund
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Background: Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. Involved in APP trafficking to and from the Golgi apparatus. It probably acts as a sorting receptor that protects APP from trafficking to late endosome and from processing into amyloid beta, thereby reducing the burden of amyloidogenic peptide formation. Involved in the regulation of smooth muscle cells migration, probably through PLAUR binding and decreased internalization.
Aliases: C11orf32 antibody, FLJ21930 antibody, FLJ39258 antibody, gp250 antibody, LDLR relative with 11 ligand binding repeats antibody, LDLR relative with 11 ligand-binding repeats antibody, Low density lipoprotein receptor relative with 11 ligand binding repeats antibody, Low-density lipoprotein receptor relative with 11 ligand-binding repeats antibody, LR 11 antibody, LR11 antibody, LRP 9 antibody, LRP9 antibody, Mosaic protein LR11 antibody, SORL 1 antibody, SORL_HUMAN antibody, SORL1 antibody, SorLA 1 antibody, SorLA antibody, SorLA-1 antibody, Sortilin related receptor antibody, Sortilin related receptor L(DLR class) A repeats containing antibody, Sortilin-related receptor antibody, Sorting protein related receptor containing LDLR class A repeats antibody, Sorting protein-related receptor containing LDLR class A repeats antibody
- UniProt
- Q92673
- Pathways
- Smooth Muscle Cell Migration
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