SNX17 Antikörper (AA 280-457) (HRP)

Produktnummer ABIN7170367

Produktdetails anti-SNX17 Antikörper (HRP)

Target: SNX17 (Sorting Nexin 17 (SNX17))

Bindungsspezifität: AA 280-457

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNX17 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Sorting nexin-17 protein (280-457AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SNX17

Target: SNX17 (Sorting Nexin 17 (SNX17))

Andere Bezeichnung: SNX17 (SNX17 Produkte)

Synonyme: snx17 antikoerper, MGC53167 antikoerper, MGC69341 antikoerper, MGC198061 antikoerper, MGC83142 antikoerper, SNX17 antikoerper, wu:fb67g03 antikoerper, wu:fb67g09 antikoerper, wu:fc27g08 antikoerper, wu:fj81d04 antikoerper, si:ch211-101l18.2 antikoerper, 5830447M19Rik antikoerper, AI790646 antikoerper, D5Ertd260e antikoerper, mKIAA0064 antikoerper, sorting nexin 17 antikoerper, sorting nexin 17 L homeolog antikoerper, snx17 antikoerper, SNX17 antikoerper, snx17.L antikoerper, Snx17 antikoerper

Hintergrund:

Background: Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).

Aliases: Similar to a putative C elegans gene encoded in cosmid F17H10 antibody, Snx17 antibody, SNX17_HUMAN antibody, Sorting nexin 17 antibody, Sorting nexin-17 antibody

UniProt: Q15036