SAMD8 Antikörper (AA 1-152)

Produktnummer ABIN7170561

Produktdetails anti-SAMD8 Antikörper

Target: SAMD8 (Sterile alpha Motif Domain Containing 8 (SAMD8))

Bindungsspezifität: AA 1-152

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAMD8 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Sphingomyelin synthase-related protein 1 protein (1-152AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SAMD8

Target: SAMD8 (Sterile alpha Motif Domain Containing 8 (SAMD8))

Andere Bezeichnung: SAMD8 (SAMD8 Produkte)

Synonyme: CG32380 antikoerper, CG8572 antikoerper, CG8576 antikoerper, Css3beta antikoerper, Dmel\\CG32380 antikoerper, dSMSr antikoerper, dmSMSr antikoerper, SMSr antikoerper, 1110053F04Rik antikoerper, 1700010P07Rik antikoerper, CG32380 gene product from transcript CG32380-RA antikoerper, sterile alpha motif domain containing 8 antikoerper, SMSr antikoerper, SAMD8 antikoerper, samd8 antikoerper, Samd8 antikoerper

Hintergrund:

Background: Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway.

Aliases: SAMD8Sphingomyelin synthase-related protein 1 antibody, SMSr antibody, EC 2.7.8.- antibody, Ceramide phosphoethanolamine synthase antibody, CPE synthase antibody, Sterile alpha motif domain-containing protein 8 antibody, SAM domain-containing protein 8 antibody

UniProt: Q96LT4