SAMD8 Antikörper (AA 1-152) (Biotin)

Produktnummer ABIN7170562

Produktdetails anti-SAMD8 Antikörper (Biotin)

Target: SAMD8 (Sterile alpha Motif Domain Containing 8 (SAMD8))

Bindungsspezifität: AA 1-152

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAMD8 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Sphingomyelin synthase-related protein 1 protein (1-152AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SAMD8

Target: SAMD8 (Sterile alpha Motif Domain Containing 8 (SAMD8))

Andere Bezeichnung: SAMD8 (SAMD8 Produkte)

Hintergrund:

Background: Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway.

Aliases: SAMD8Sphingomyelin synthase-related protein 1 antibody, SMSr antibody, EC 2.7.8.- antibody, Ceramide phosphoethanolamine synthase antibody, CPE synthase antibody, Sterile alpha motif domain-containing protein 8 antibody, SAM domain-containing protein 8 antibody

UniProt: Q96LT4