SKA3 Antikörper (AA 101-195)
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- Target Alle SKA3 Antikörper anzeigen
- SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))
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Bindungsspezifität
- AA 101-195
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SKA3 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Spindle and kinetochore-associated protein 3 protein (101-195AA)
- Isotyp
- IgG
- Top Product
- Discover our top product SKA3 Primärantikörper
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- Applikationshinweise
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))
- Andere Bezeichnung
- SKA3 (SKA3 Produkte)
- Hintergrund
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Background: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:19289083, PubMed:19360002, PubMed:23085020). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083, PubMed:19360002). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:19289083). In the complex, it mediates the microtubule-stimulated oligomerization (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020).
Aliases: C13orf3 antibody, RAMA1 antibody, SKA3 antibody, SKA3_HUMAN antibody, Spindle and kinetochore associated complex subunit 3 antibody, Spindle and kinetochore-associated protein 3 antibody
- UniProt
- Q8IX90
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