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U2AF2 Antikörper (AA 124-246)

U2AF59 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7170633
  • Target Alle U2AF2 (U2AF59) Antikörper anzeigen
    U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
    Bindungsspezifität
    • 9
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 124-246
    Reaktivität
    • 45
    • 24
    • 17
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 44
    • 1
    Kaninchen
    Klonalität
    • 43
    • 2
    Polyklonal
    Konjugat
    • 22
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser U2AF2 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 12
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Splicing factor U2AF 65 kDa subunit protein (124-246AA)
    Isotyp
    IgG
    Top Product
    Discover our top product U2AF59 Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
    Andere Bezeichnung
    U2AF2 (U2AF59 Produkte)
    Hintergrund

    Background: Necessary for the splicing of pre-mRNA. By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-terminal domain (CTD), and thereby pre-mRNA, may couple transcription to splicing (PubMed:21536736). Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Represses the splicing of MAPT/Tau exon 10.

    Aliases: hU2AF(65) antibody, hU2AF65 antibody, Splicing factor U2AF 65 kDa subunit antibody, U2 (RNU2) small nuclear RNA auxiliary factor 2 antibody, U2 auxiliary factor 65 kDa subunit antibody, U2 small nuclear ribonucleoprotein auxiliary factor (65kD) antibody, U2 small nuclear RNA auxiliary factor 2 antibody, U2 snRNP auxiliary factor large subunit antibody, U2af2 antibody, U2AF2_HUMAN antibody, U2AF65 antibody

    UniProt
    P26368
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