SART3 Antikörper (AA 600-900) (HRP)
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- Target Alle SART3 Antikörper anzeigen
- SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))
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Bindungsspezifität
- AA 600-900
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SART3 Antikörper ist konjugiert mit HRP
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Applikation
- ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Squamous cell carcinoma antigen recognized by T-cells 3 protein (600-900AA)
- Isotyp
- IgG
- Top Product
- Discover our top product SART3 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))
- Andere Bezeichnung
- SART3 (SART3 Produkte)
- Synonyme
- SART3 antikoerper, DKFZp469J2418 antikoerper, si:ch211-191d15.4 antikoerper, wu:fc51h03 antikoerper, DSAP1 antikoerper, P100 antikoerper, RP11-13G14 antikoerper, TIP110 antikoerper, p110 antikoerper, p110(nrb) antikoerper, AU045857 antikoerper, mKIAA0156 antikoerper, squamous cell carcinoma antigen recognized by T-cells 3 antikoerper, squamous cell carcinoma antigen recognized by T-cells 3 L homeolog antikoerper, squamous cell carcinoma antigen recognized by T cells 3 antikoerper, SART3 antikoerper, sart3 antikoerper, sart3.L antikoerper, Sart3 antikoerper
- Hintergrund
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Background: U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation (PubMed:12032085). Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites (PubMed:14749385). May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. Recruits USP4 to ubiquitinated PRPF3 within the U4/U5/U6 tri-snRNP complex, promoting PRPF3 deubiquitination and thereby regulating the spliceosome U4/U5/U6 tri-snRNP spliceosomal complex disassembly (PubMed:20595234). May also recruit the deubiquitinase USP15 to histone H2B and mediate histone deubiquitination, thereby regulating gene expression and/or DNA repair (PubMed:24526689). May play a role in hematopoiesis probably through transcription regulation of specific genes including MYC (By similarity).
Aliases: DSAP1 antibody, hSART 3 antibody, hSART-3 antibody, P100 antibody, P110 antibody, p110(nrb) antibody, RP11 13G14 antibody, SART 3 antibody, SART-3 antibody, SART3 antibody, SART3_HUMAN antibody, Squamous cell carcinoma antigen recognized by T cells 3 antibody, Squamous cell carcinoma antigen recognized by T-cells 3 antibody, Tat interacting protein of 110 kDa antibody, Tat-interacting protein of 110 kDa antibody, Tip110 antibody
- UniProt
- Q15020
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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