STAMBP Antikörper (AA 1-424)
-
- Target Alle STAMBP Antikörper anzeigen
- STAMBP (STAM Binding Protein (STAMBP))
-
Bindungsspezifität
- AA 1-424
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser STAMBP Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human STAM-binding protein (1-424AA)
- Isotyp
- IgG
- Top Product
- Discover our top product STAMBP Primärantikörper
-
-
- Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- STAMBP (STAM Binding Protein (STAMBP))
- Andere Bezeichnung
- STAMBP (STAMBP Produkte)
- Synonyme
- AMSH antikoerper, 5330424L14Rik antikoerper, 5730422L11Rik antikoerper, AW107289 antikoerper, Amsh antikoerper, mKIAA4198 antikoerper, stambp antikoerper, zgc:66147 antikoerper, STAM binding protein antikoerper, Stam binding protein antikoerper, STAM binding protein a antikoerper, STAMBP antikoerper, Stambp antikoerper, stambpa antikoerper
- Hintergrund
-
Background: Zinc metalloprotease that specifically cleaves \\\'Lys-63\\\'-linked polyubiquitin chains. Does not cleave \\\'Lys-48\\\'-linked polyubiquitin chains.Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization .Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.
Aliases: AMSH antibody, Associated molecule with the SH3 domain of STAM antibody, Endosome associated ubiquitin isopeptidase antibody, Endosome-associated ubiquitin isopeptidase antibody, MGC126516 antibody, MGC126518 antibody, MICCAP antibody, STABP_HUMAN antibody, STAM binding protein antibody, STAM-binding protein antibody, Stambp antibody
- UniProt
- O95630
-