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STAMBP Antikörper (AA 1-424)

STAMBP Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7170686
  • Target Alle STAMBP Antikörper anzeigen
    STAMBP (STAM Binding Protein (STAMBP))
    Bindungsspezifität
    • 15
    • 11
    • 8
    • 7
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 1-424
    Reaktivität
    • 44
    • 31
    • 20
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 56
    • 4
    Kaninchen
    Klonalität
    • 57
    • 3
    Polyklonal
    Konjugat
    • 24
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser STAMBP Antikörper ist unkonjugiert
    Applikation
    • 35
    • 22
    • 18
    • 13
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human STAM-binding protein (1-424AA)
    Isotyp
    IgG
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  • Applikationshinweise
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    STAMBP (STAM Binding Protein (STAMBP))
    Andere Bezeichnung
    STAMBP (STAMBP Produkte)
    Synonyme
    AMSH antikoerper, 5330424L14Rik antikoerper, 5730422L11Rik antikoerper, AW107289 antikoerper, Amsh antikoerper, mKIAA4198 antikoerper, stambp antikoerper, zgc:66147 antikoerper, STAM binding protein antikoerper, Stam binding protein antikoerper, STAM binding protein a antikoerper, STAMBP antikoerper, Stambp antikoerper, stambpa antikoerper
    Hintergrund

    Background: Zinc metalloprotease that specifically cleaves \\\'Lys-63\\\'-linked polyubiquitin chains. Does not cleave \\\'Lys-48\\\'-linked polyubiquitin chains.Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization .Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.

    Aliases: AMSH antibody, Associated molecule with the SH3 domain of STAM antibody, Endosome associated ubiquitin isopeptidase antibody, Endosome-associated ubiquitin isopeptidase antibody, MGC126516 antibody, MGC126518 antibody, MICCAP antibody, STABP_HUMAN antibody, STAM binding protein antibody, STAM-binding protein antibody, Stambp antibody

    UniProt
    O95630
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