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STIM1 Antikörper (AA 2-350)

STIM1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7170833
  • Target Alle STIM1 Antikörper anzeigen
    STIM1 (Stromal Interaction Molecule 1 (STIM1))
    Bindungsspezifität
    • 15
    • 15
    • 15
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-350
    Reaktivität
    • 70
    • 55
    • 25
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 74
    • 9
    • 1
    • 1
    Kaninchen
    Klonalität
    • 69
    • 16
    Polyklonal
    Konjugat
    • 37
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser STIM1 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 30
    • 26
    • 26
    • 24
    • 18
    • 10
    • 10
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Stromal interaction molecule 1 protein (2-350AA)
    Isotyp
    IgG
    Top Product
    Discover our top product STIM1 Primärantikörper
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    STIM1 (Stromal Interaction Molecule 1 (STIM1))
    Andere Bezeichnung
    STIM1 (STIM1 Produkte)
    Synonyme
    stim1 antikoerper, MGC76045 antikoerper, STIM1 antikoerper, si:dkey-24p1.5 antikoerper, MGC154748 antikoerper, si:ch211-112l17.2 antikoerper, Stim1 antikoerper, D11S4896E antikoerper, GOK antikoerper, TAM antikoerper, SIM antikoerper, stromal interaction molecule 1 antikoerper, stromal interaction molecule 1a antikoerper, stromal interaction molecule 1 L homeolog antikoerper, stromal interaction molecule 1b antikoerper, STIM1 antikoerper, stim1 antikoerper, stim1a antikoerper, stim1.L antikoerper, stim1b antikoerper, Stim1 antikoerper
    Hintergrund

    Background: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores (PubMed:15866891, PubMed:16005298, PubMed:16208375, PubMed:16537481, PubMed:16733527, PubMed:16766533, PubMed:16807233, PubMed:18854159, PubMed:19249086, PubMed:22464749, PubMed:24069340, PubMed:24351972, PubMed:24591628, PubMed:26322679, PubMed:25326555). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1 (PubMed:16208375, PubMed:16537481). Involved in enamel formation (PubMed:24621671). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch (PubMed:26322679).

    Aliases: D11S4896E antibody, GOK antibody, OTTHUMP00000164512 antibody, OTTHUMP00000229140 antibody, OTTHUMP00000230742 antibody, SIM antibody, STIM 1 antibody, STIM1 antibody, Stim1 stromal interaction molecule 1 antibody, STIM1_HUMAN antibody, STIM1L antibody, Stromal interaction molecule 1 antibody

    UniProt
    Q13586
    Pathways
    T-Zell Rezeptor Signalweg, BCR Signaling
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