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Stim2 Antikörper (AA 471-656) (Biotin)

Stim2 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN7170838
  • Target Alle Stim2 Antikörper anzeigen
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    Bindungsspezifität
    • 10
    • 8
    • 7
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 471-656
    Reaktivität
    • 37
    • 14
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 35
    • 1
    • 1
    Kaninchen
    Klonalität
    • 37
    Polyklonal
    Konjugat
    • 22
    • 5
    • 3
    • 3
    • 2
    • 2
    Dieser Stim2 Antikörper ist konjugiert mit Biotin
    Applikation
    • 34
    • 26
    • 19
    • 5
    • 4
    • 4
    • 2
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Stromal interaction molecule 2 protein (471-656AA)
    Isotyp
    IgG
    Top Product
    Discover our top product Stim2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    Andere Bezeichnung
    STIM2 (Stim2 Produkte)
    Synonyme
    STIM2 antikoerper, stromal interaction molecule 2 antikoerper, STIM2 antikoerper, stim2 antikoerper, Stim2 antikoerper
    Hintergrund

    Background: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx.

    Aliases: FLJ39527 antibody, KIAA1482 antibody, STIM 2 antibody, STIM2 antibody, STIM2_HUMAN antibody, Stromal interaction molecule 2 antibody

    UniProt
    Q9P246
    Pathways
    T-Zell Rezeptor Signalweg, BCR Signaling
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