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SMC6 Antikörper (AA 309-450) (FITC)

SMC6 Reaktivität: Human Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN7170876
  • Target Alle SMC6 Antikörper anzeigen
    SMC6 (SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6))
    Bindungsspezifität
    • 15
    • 5
    • 3
    • 2
    • 1
    • 1
    AA 309-450
    Reaktivität
    • 20
    • 19
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 33
    • 2
    Kaninchen
    Klonalität
    • 33
    • 2
    Polyklonal
    Konjugat
    • 13
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SMC6 Antikörper ist konjugiert mit FITC
    Applikation
    Bitte anfragen
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Structural maintenance of chromosomes protein 6 protein (309-450AA)
    Isotyp
    IgG
    Top Product
    Discover our top product SMC6 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SMC6 (SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6))
    Andere Bezeichnung
    SMC6 (SMC6 Produkte)
    Synonyme
    SMC6L1 antikoerper, SMC-6 antikoerper, hSMC6 antikoerper, 2810489L22Rik antikoerper, 3830418C19Rik antikoerper, AA990493 antikoerper, AU018782 antikoerper, AW742439 antikoerper, Smc6l1 antikoerper, mKIAA4103 antikoerper, structural maintenance of chromosomes 6 antikoerper, SMC6 antikoerper, smc6 antikoerper, Smc6 antikoerper
    Hintergrund

    Background: Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies. SMC5-SMC6 complex may prevent transcription of episomal DNA, such as circular viral DNA genome (PubMed:26983541).

    Aliases: FLJ22116 antibody, FLJ35534 antibody, hSMC6 antibody, SMC 6 antibody, SMC protein 6 antibody, SMC-6 antibody, SMC6 antibody, SMC6 protein antibody, SMC6 structural maintenance of chromosomes 6 like 1 antibody, SMC6_HUMAN antibody, Smc6l1 antibody, Structural maintenance of chromosomes 6 antibody, Structural maintenance of chromosomes 6 like 1 antibody, Structural maintenance of chromosomes protein 6 antibody

    UniProt
    Q96SB8
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