SOCS2 Antikörper (AA 1-198)

Produktnummer ABIN7170996

Produktdetails anti-SOCS2 Antikörper

Target: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Bindungsspezifität: AA 1-198

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOCS2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Suppressor of cytokine signaling 2 protein (1-198AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SOCS2

Target: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Andere Bezeichnung: SOCS2 (SOCS2 Produkte)

Synonyme: CIS2 antikoerper, Cish2 antikoerper, SOCS-2 antikoerper, SSI-2 antikoerper, SSI2 antikoerper, STATI2 antikoerper, Cish1 antikoerper, Socs-1 antikoerper, Socs-2 antikoerper, si:dkey-202b22.1 antikoerper, socs2 antikoerper, cis2 antikoerper, ssi2 antikoerper, cish2 antikoerper, ssi-2 antikoerper, socs-2 antikoerper, stati2 antikoerper, 8030460M17 antikoerper, AI527257 antikoerper, AW108012 antikoerper, D130043N08Rik antikoerper, JAB antikoerper, hg antikoerper, Cradd antikoerper, Socs2 antikoerper, suppressor of cytokine signaling 2 antikoerper, suppressor of cytokine signaling 1 antikoerper, death domain-containing protein CRADD antikoerper, suppressor of cytokine signaling 2 S homeolog antikoerper, SOCS2 antikoerper, Socs1 antikoerper, Socs2 antikoerper, socs2 antikoerper, LOC100716104 antikoerper, socs2.S antikoerper

Hintergrund:

Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Aliases: CIS 2 antibody, CIS-2 antibody, CIS2 antibody, Cish 2 antibody, Cish2 antibody, Cytokine inducible SH2 protein 2 antibody, Cytokine-inducible SH2 protein 2 antibody, SOCS 2 antibody, SOCS-2 antibody, Socs2 antibody, SOCS2_HUMAN antibody, SSI 2 antibody, SSI-2 antibody, SSI2 antibody, STAT induced STAT inhibitor 2 antibody, STAT-induced STAT inhibitor 2 antibody, STATI 2 antibody, STATI2 antibody, Suppressor of cytokine signaling 2 antibody

UniProt: O14508

Pathways: JAK-STAT Signalweg, Response to Growth Hormone Stimulus