SOCS7 Antikörper (AA 6-165)

Produktnummer ABIN7171009

Produktdetails anti-SOCS7 Antikörper

Target: SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))

Bindungsspezifität: AA 6-165

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOCS7 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Kreuzreaktivität: Human, Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Suppressor of cytokine signaling 7 protein (6-165AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SOCS7

Target: SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))

Andere Bezeichnung: SOCS7 (SOCS7 Produkte)

Hintergrund:

Background: Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).

Aliases: Ash and phospholipase C gamma-binding protein antibody, NAP 4 antibody, NAP 4 Fragment antibody, NAP-4 antibody, NAP4 antibody, Nck antibody, Nck Ash and phospholipase C binding protein antibody, Nck Ash and phospholipase C gamma binding protein antibody, Nck associated protein 4 antibody, Nck-associated protein 4 antibody, NCKAP4 antibody, SH2 domain containing SOCS box protein antibody, SOCS 7 antibody, SOCS-7 antibody, SOCS4 antibody, SOCS6 antibody, Socs7 antibody, SOCS7_HUMAN antibody, Suppressor of cytokine signaling 7 antibody

UniProt: O14512