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TPX2 Antikörper (AA 160-320)

TPX2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7171526
  • Target Alle TPX2 Antikörper anzeigen
    TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 160-320
    Reaktivität
    • 63
    • 35
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 63
    • 15
    Kaninchen
    Klonalität
    • 63
    • 15
    Polyklonal
    Konjugat
    • 34
    • 7
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TPX2 Antikörper ist unkonjugiert
    Applikation
    • 68
    • 38
    • 13
    • 13
    • 12
    • 10
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Targeting protein for Xklp2 protein (160-320AA)
    Isotyp
    IgG
    Top Product
    Discover our top product TPX2 Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
    Andere Bezeichnung
    TPX2 (TPX2 Produkte)
    Synonyme
    C20orf1 antikoerper, C20orf2 antikoerper, DIL-2 antikoerper, DIL2 antikoerper, FLS353 antikoerper, GD:C20orf1 antikoerper, HCA519 antikoerper, HCTP4 antikoerper, REPP86 antikoerper, p100 antikoerper, 2610005B21Rik antikoerper, TPX2 antikoerper, dil-2 antikoerper, dil2 antikoerper, hctp4 antikoerper, repp86 antikoerper, tpx2 antikoerper, TPX2, microtubule nucleation factor antikoerper, TPX2, microtubule-associated antikoerper, TPX2, microtubule-associated, homolog (Xenopus laevis) antikoerper, TPX2, microtubule-associated S homeolog antikoerper, TPX2, microtubule-associated L homeolog antikoerper, TPX2 antikoerper, Tpx2 antikoerper, tpx2.S antikoerper, tpx2.L antikoerper
    Hintergrund

    Background: Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules (PubMed:18663142, PubMed:19208764). Activates AURKA by promoting its autophosphorylation at \\\'Thr-288\\\' and protects this residue against dephosphorylation (PubMed:18663142, PubMed:19208764). TPX2 is inactivated upon binding to importin-alpha (PubMed:26165940). At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation (PubMed:26165940).

    Aliases: C20ORF1 antibody, C20orf2 antibody, Chromosome 20 Open Reading Frame 1 antibody, Differentially expressed in cancerous and non-cancerous lung cells 2 antibody, Differentially expressed in cancerous and noncancerous lung cells 2 antibody, Differentially expressed in lung cells 2 antibody, Differentially expressed in lung cells antibody, DIL 2 antibody, DIL-2 antibody, DIL2 antibody, FLS353 antibody, GD:C20orf1 antibody, HCA 519 antibody, HCA519 antibody, HCTP 4 antibody, HCTP4 antibody, Hepatocellular carcinoma associated antigen 519 antibody, Hepatocellular carcinoma-associated antigen 519 antibody, p100 antibody, Preferentially expressed in colorectal cancer antibody, Protein fls353 antibody, REPP 86 antibody, repp86 antibody, Restricted expression proliferation associated protein 100 antibody, Restricted expression proliferation-associated protein 100 antibody, Targeting protein for Xklp2 antibody, TPX 2 antibody, TPX2 antibody, TPX2 microtubule associated homolog antibody, TPX2 microtubule associated protein homolog antibody, TPX2 microtubule nucleation factor antibody, TPX2_HUMAN antibody

    UniProt
    Q9ULW0
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