TPX2 Antikörper (AA 160-320)
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- Target Alle TPX2 Antikörper anzeigen
- TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
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Bindungsspezifität
- AA 160-320
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TPX2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Targeting protein for Xklp2 protein (160-320AA)
- Isotyp
- IgG
- Top Product
- Discover our top product TPX2 Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
- Andere Bezeichnung
- TPX2 (TPX2 Produkte)
- Synonyme
- C20orf1 antikoerper, C20orf2 antikoerper, DIL-2 antikoerper, DIL2 antikoerper, FLS353 antikoerper, GD:C20orf1 antikoerper, HCA519 antikoerper, HCTP4 antikoerper, REPP86 antikoerper, p100 antikoerper, 2610005B21Rik antikoerper, TPX2 antikoerper, dil-2 antikoerper, dil2 antikoerper, hctp4 antikoerper, repp86 antikoerper, tpx2 antikoerper, TPX2, microtubule nucleation factor antikoerper, TPX2, microtubule-associated antikoerper, TPX2, microtubule-associated, homolog (Xenopus laevis) antikoerper, TPX2, microtubule-associated S homeolog antikoerper, TPX2, microtubule-associated L homeolog antikoerper, TPX2 antikoerper, Tpx2 antikoerper, tpx2.S antikoerper, tpx2.L antikoerper
- Hintergrund
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Background: Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules (PubMed:18663142, PubMed:19208764). Activates AURKA by promoting its autophosphorylation at \\\'Thr-288\\\' and protects this residue against dephosphorylation (PubMed:18663142, PubMed:19208764). TPX2 is inactivated upon binding to importin-alpha (PubMed:26165940). At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation (PubMed:26165940).
Aliases: C20ORF1 antibody, C20orf2 antibody, Chromosome 20 Open Reading Frame 1 antibody, Differentially expressed in cancerous and non-cancerous lung cells 2 antibody, Differentially expressed in cancerous and noncancerous lung cells 2 antibody, Differentially expressed in lung cells 2 antibody, Differentially expressed in lung cells antibody, DIL 2 antibody, DIL-2 antibody, DIL2 antibody, FLS353 antibody, GD:C20orf1 antibody, HCA 519 antibody, HCA519 antibody, HCTP 4 antibody, HCTP4 antibody, Hepatocellular carcinoma associated antigen 519 antibody, Hepatocellular carcinoma-associated antigen 519 antibody, p100 antibody, Preferentially expressed in colorectal cancer antibody, Protein fls353 antibody, REPP 86 antibody, repp86 antibody, Restricted expression proliferation associated protein 100 antibody, Restricted expression proliferation-associated protein 100 antibody, Targeting protein for Xklp2 antibody, TPX 2 antibody, TPX2 antibody, TPX2 microtubule associated homolog antibody, TPX2 microtubule associated protein homolog antibody, TPX2 microtubule nucleation factor antibody, TPX2_HUMAN antibody
- UniProt
- Q9ULW0
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