TRF1 Antikörper (AA 260-439)

Produktnummer ABIN7171727

Produktdetails anti-TRF1 Antikörper

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Bindungsspezifität: AA 260-439

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRF1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Telomeric repeat-binding factor 1 protein (260-439AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TRF1

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Andere Bezeichnung: TERF1 (TERF1 Produkte)

Synonyme: PIN2 antikoerper, TRBF1 antikoerper, TRF antikoerper, TRF1 antikoerper, hTRF1-AS antikoerper, t-TRF1 antikoerper, wu:fb74c04 antikoerper, TERF1 antikoerper, DKFZp459A0713 antikoerper, Pin2 antikoerper, Trbf1 antikoerper, Trf1 antikoerper, terf1 antikoerper, trf1 antikoerper, telomeric repeat binding factor 1 antikoerper, telomeric repeat binding factor (NIMA-interacting) 1 antikoerper, telomeric repeat binding factor (NIMA-interacting) 1 L homeolog antikoerper, TERF1 antikoerper, Terf1 antikoerper, terf1 antikoerper, Trf1 antikoerper, terf1.L antikoerper

Hintergrund:

Background: Binds the telomeric double-stranded 5\\\'-TTAGGG-3\\\' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5\\\'-TTAGGG-3\\\' repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.

Aliases: hTRF1 AS antibody, NIMA interacting protein 2 antibody, NIMA-interacting protein 2 antibody, PIN 2 antibody, PIN2 antibody, t TRF1 antibody, Telomeric protein Pin2 antibody, Telomeric protein Pin2/TRF1 antibody, Telomeric repeat binding factor (NIMA interacting) 1 antibody, Telomeric repeat binding factor 1 antibody, Telomeric repeat binding protein 1 antibody, Telomeric repeat-binding factor 1 antibody, TERF 1 antibody, Terf1 antibody, TERF1_HUMAN antibody, TRBF 1 antibody, TRBF1 antibody, TRF 1 antibody, TRF antibody, TTAGGG repeat binding factor 1 antibody, TTAGGG repeat-binding factor 1 antibody

UniProt: P54274

Pathways: Zellzyklus, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity