Tenascin N Antikörper (AA 441-556)

Produktnummer ABIN7171746

Produktdetails anti-Tenascin N Antikörper

Target: Tenascin N (TNN)

Bindungsspezifität: AA 441-556

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tenascin N Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Tenascin-N protein (441-556AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Tenascin N

Target: Tenascin N (TNN)

Andere Bezeichnung: TNN (TNN Produkte)

Synonyme: TNW antikoerper, tenascin-N antikoerper, TNN antikoerper, TN-W antikoerper, Tnw antikoerper, tenascin-W antikoerper, tenascin N antikoerper, Tnn antikoerper, TNN antikoerper

Hintergrund:

Background: Extracellular matrix protein that seems to be a ligand for ITGA8:ITGB1, ITGAV:ITGB1 and ITGA4:ITGB1 (By similarity) (PubMed:17909022). Involved in neurite outgrowth and cell migration in hippocampal explants (By similarity). During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling (By similarity). In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (PubMed:19884327). Expressed in most mammary tumors, may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells (PubMed:17909022).

Aliases: TNN antibody, TNW antibody, Tenascin-N antibody, TN-N antibody, Tenascin-W antibody, TN-W antibody

UniProt: Q9UQP3

Pathways: ACE Inhibitor Pathway