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TXNIP Antikörper (AA 299-381)

TXNIP Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7172027
  • Target Alle TXNIP Antikörper anzeigen
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    Bindungsspezifität
    • 16
    • 9
    • 8
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 299-381
    Reaktivität
    • 62
    • 48
    • 33
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 71
    • 5
    Kaninchen
    Klonalität
    • 63
    • 13
    Polyklonal
    Konjugat
    • 30
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TXNIP Antikörper ist unkonjugiert
    Applikation
    • 53
    • 26
    • 15
    • 14
    • 14
    • 8
    • 8
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    ELISA, Immunofluorescence (IF)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Thioredoxin-interacting protein (299-381AA)
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    Recommended dilution: IF:1:50-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    Andere Bezeichnung
    TXNIP (TXNIP Produkte)
    Hintergrund

    Background: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).

    Aliases: EST01027 antibody, HHCPA78 antibody, THIF antibody, Thioredoxin binding protein 2 antibody, Thioredoxin interacting protein antibody, Thioredoxin-binding protein 2 antibody, Thioredoxin-interacting protein antibody, TXNIP antibody, TXNIP_HUMAN antibody, Upregulated by 1,25 dihydroxyvitamin D 3 antibody, VDUP1 antibody, Vitamin D3 up-regulated protein 1 antibody

    UniProt
    Q9H3M7
    Pathways
    Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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