THOC6 Antikörper (AA 56-315)
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- Target Alle THOC6 Antikörper anzeigen
- THOC6 (THO Complex 6 Homolog (THOC6))
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Bindungsspezifität
- AA 56-315
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser THOC6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human THO complex subunit 6 homolog protein (56-315AA)
- Isotyp
- IgG
- Top Product
- Discover our top product THOC6 Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- THOC6 (THO Complex 6 Homolog (THOC6))
- Andere Bezeichnung
- THOC6 (THOC6 Produkte)
- Synonyme
- WDR58 antikoerper, fSAP35 antikoerper, F830014G06Rik antikoerper, Wdr58 antikoerper, Pdrp antikoerper, zgc:101618 antikoerper, thoc6 antikoerper, THO complex 6 antikoerper, THO complex 6 homolog (Drosophila) antikoerper, THO complex 6 L homeolog antikoerper, THOC6 antikoerper, Thoc6 antikoerper, thoc6 antikoerper, thoc6.L antikoerper
- Hintergrund
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Background: Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5\' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi\'s sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. Plays a role in apoptosis negative control involved in brain development.
Aliases: THOC6 antibody, WDR58 antibody, PSEC0006 antibody, THO complex subunit 6 homolog antibody, Functional spliceosome-associated protein 35 antibody, fSAP35 antibody, WD repeat-containing protein 58 antibody
- UniProt
- Q86W42
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