THOC6 Antikörper (AA 56-315) (HRP)

Produktnummer ABIN7172066

Produktdetails anti-THOC6 Antikörper (HRP)

Target: THOC6 (THO Complex 6 Homolog (THOC6))

Bindungsspezifität: AA 56-315

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser THOC6 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human THO complex subunit 6 homolog protein (56-315AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu THOC6

Target: THOC6 (THO Complex 6 Homolog (THOC6))

Andere Bezeichnung: THOC6 (THOC6 Produkte)

Synonyme: WDR58 antikoerper, fSAP35 antikoerper, F830014G06Rik antikoerper, Wdr58 antikoerper, Pdrp antikoerper, zgc:101618 antikoerper, thoc6 antikoerper, THO complex 6 antikoerper, THO complex 6 homolog (Drosophila) antikoerper, THO complex 6 L homeolog antikoerper, THOC6 antikoerper, Thoc6 antikoerper, thoc6 antikoerper, thoc6.L antikoerper

Hintergrund:

Background: Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5\' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi\'s sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. Plays a role in apoptosis negative control involved in brain development.

Aliases: THOC6 antibody, WDR58 antibody, PSEC0006 antibody, THO complex subunit 6 homolog antibody, Functional spliceosome-associated protein 35 antibody, fSAP35 antibody, WD repeat-containing protein 58 antibody

UniProt: Q86W42