TLR1 Antikörper (AA 25-580)

Produktnummer ABIN7172261

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TLR1 in IHC, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TLR1 Antikörper (AA 25-580) (ABIN7172261)

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-TLR1 Antikörper

Bindungsspezifität: AA 25-580

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Toll-like receptor 1 protein (25-580AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TLR1

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Andere Bezeichnung: TLR1

Hintergrund:

Background: Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Aliases: CD281 antibody, CD281 antigen antibody, KIAA0012 antibody, LPRS5 antibody, rsc786 antibody, TIL antibody, TIL. LPRS5 antibody, Tlr1 antibody, TLR1_HUMAN antibody, Toll (Drosophila) homolog antibody, Toll like receptor 1 antibody, Toll-like receptor 1 antibody, Toll/interleukin-1 receptor-like protein antibody

UniProt: Q15399

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades