TNIK Antikörper (AA 523-714)
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- Target Alle TNIK Antikörper anzeigen
- TNIK (TRAF2 and NCK Interacting Kinase (TNIK))
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Bindungsspezifität
- AA 523-714
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TNIK Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human TRAF2 and NCK-interacting protein kinase protein (523-714AA)
- Isotyp
- IgG
- Top Product
- Discover our top product TNIK Primärantikörper
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- TNIK (TRAF2 and NCK Interacting Kinase (TNIK))
- Andere Bezeichnung
- TNIK (TNIK Produkte)
- Hintergrund
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Background: Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.
Aliases: EC 2.7.11.1 antibody, KIAA0551 antibody, Tnik antibody, TNIK_HUMAN antibody, Traf2 and NCK interacting kinase antibody, Traf2 and NCK-interacting protein kinase antibody
- UniProt
- Q9UKE5
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