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TFEB Antikörper (AA 1-220)

TFEB Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7172534
  • Target Alle TFEB Antikörper anzeigen
    TFEB (Transcription Factor EB (TFEB))
    Bindungsspezifität
    • 16
    • 9
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-220
    Reaktivität
    • 61
    • 30
    • 26
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 54
    • 7
    Kaninchen
    Klonalität
    • 54
    • 6
    Polyklonal
    Konjugat
    • 37
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TFEB Antikörper ist unkonjugiert
    Applikation
    • 55
    • 30
    • 14
    • 13
    • 13
    • 11
    • 9
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Transcription factor EB protein (1-220AA)
    Isotyp
    IgG
    Top Product
    Discover our top product TFEB Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    TFEB (Transcription Factor EB (TFEB))
    Andere Bezeichnung
    TFEB (TFEB Produkte)
    Synonyme
    TFEB antikoerper, tcfeb antikoerper, MGC145796 antikoerper, alphatfeb antikoerper, ALPHATFEB antikoerper, BHLHE35 antikoerper, TCFEB antikoerper, Tcfeb antikoerper, bHLHe35 antikoerper, transcription factor EB antikoerper, TFEB antikoerper, tfeb antikoerper, Tfeb antikoerper
    Hintergrund

    Background: Transcription factor that specifically recognizes and binds E-box sequences (5\\\'-CANNTG-3\\\'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5\\\'-GTCACGTGAC-3\\\') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Acts as a positive regulator of autophagy by promoting expression of genes involved in autophagy. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.

    Aliases: Alpha TFEB antibody, AlphaTFEB antibody, bHLHe35 antibody, Class E basic helix-loop-helix protein 35 antibody, T cell transcription factor EB antibody, TCFEB antibody, TFEB antibody, TFEB_HUMAN antibody, Transcription factor EB antibody

    UniProt
    P19484
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