RFX3 Antikörper (AA 201-413)

Produktnummer ABIN7172598

Produktdetails anti-RFX3 Antikörper

Target: RFX3 (Regulatory Factor X 3 (RFX3))

Bindungsspezifität: AA 201-413

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RFX3 Antikörper ist unkonjugiert

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Transcription factor RFX3 protein (201-413AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RFX3

Target: RFX3 (Regulatory Factor X 3 (RFX3))

Andere Bezeichnung: RFX3 (RFX3 Produkte)

Synonyme: ba32f11.1 antikoerper, C230093O12Rik antikoerper, MRFX3 antikoerper, zgc:153245 antikoerper, regulatory factor X3 antikoerper, regulatory factor X, 3 (influences HLA class II expression) antikoerper, Rfx3 antikoerper, rfx3 antikoerper, RFX3 antikoerper

Hintergrund:

Background: Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development. Essential for the differentiation of nodal monocilia and left-right asymmetry specification during embryogenesis. Required for the biogenesis of motile cilia by governing growth and beating efficiency of motile cells. Also required for ciliated ependymal cell differentiation. Regulates the expression of genes involved in ciliary assembly (DYNC2LI1, FOXJ1 and BBS4) and genes involved in ciliary motility (DNAH11, DNAH9 and DNAH5). Together with RFX6, participates in the differentiation of 4 of the 5 islet cell types during endocrine pancreas development, with the exception of pancreatic PP (polypeptide-producing) cells. Regulates transcription by forming a heterodimer with another RFX protein and binding to the X-box in the promoter of target genes. Acts as a transcription factor. Represses transcription of MAP1A in non-neuronal cells but not in neuronal cells.

Aliases: bA32F11.1 antibody, DNA binding protein RFX3 antibody, Regulatory factor X 3 antibody, Regulatory factor X, 3 (influences HLA class II expression) antibody, RFX3 antibody, RFX3_HUMAN antibody, Transcription factor RFX3 antibody

UniProt: P48380