P4HTM Antikörper (AA 82-563)

Produktnummer ABIN7172999

Produktdetails anti-P4HTM Antikörper

Target: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Bindungsspezifität: AA 82-563

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser P4HTM Antikörper ist unkonjugiert

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Transmembrane prolyl 4-hydroxylase protein (82-563AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu P4HTM

Target: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Andere Bezeichnung: P4HTM (P4HTM Produkte)

Synonyme: Ph-4 antikoerper, RGD1311848 antikoerper, EGLN4 antikoerper, HIFPH4 antikoerper, P4H-TM antikoerper, PH-4 antikoerper, PH4 antikoerper, PHD4 antikoerper, 4933406E20Rik antikoerper, AI853847 antikoerper, BB128974 antikoerper, prolyl 4-hydroxylase, transmembrane antikoerper, prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) antikoerper, shisa family member 5 antikoerper, P4htm antikoerper, P4HTM antikoerper, SHISA5 antikoerper

Hintergrund:

Background: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at \'Pro-402\' and \'Pro-564\'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

Aliases: EGLN4 antibody, HIF PH4 antibody, HIF Prolyl Hydroxylase 4 antibody, HIF prolyl hydroxylase PH 4 antibody, HIF prolyl hydroxylase PH4 antibody, HIF-PH4 antibody, HIF-prolyl hydroxylase 4 antibody, HIFPH4 antibody, HPH 4 antibody, HPH-4 antibody, Hypoxia inducible factor prolyl 4 hydroxylase antibody, Hypoxia-inducible factor prolyl hydroxylase 4 antibody, P4H with transmembrane domain antibody, P4H-TM antibody, P4htm antibody, P4HTM_HUMAN antibody, PH 4 antibody, PH4 antibody, PHD 4 antibody, Proline 4 hydroxylase antibody, prolyl 4-hydroxylase antibody, Transmembrane prolyl 4-hydroxylase antibody

UniProt: Q9NXG6