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TCHP Antikörper (AA 1-498)

TCHP Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7173373
  • Target Alle TCHP Antikörper anzeigen
    TCHP (Trichoplein, Keratin Filament Binding (TCHP))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    AA 1-498
    Reaktivität
    • 30
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 29
    Kaninchen
    Klonalität
    • 29
    Polyklonal
    Konjugat
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TCHP Antikörper ist unkonjugiert
    Applikation
    • 19
    • 17
    • 13
    • 13
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Trichoplein keratin filament-binding protein (1-498AA)
    Isotyp
    IgG
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    TCHP (Trichoplein, Keratin Filament Binding (TCHP))
    Andere Bezeichnung
    TCHP (TCHP Produkte)
    Synonyme
    TpMs antikoerper, A930031F18Rik antikoerper, AV279199 antikoerper, RGD1310813 antikoerper, zgc:136634 antikoerper, trichoplein keratin filament binding antikoerper, trichoplein, keratin filament binding antikoerper, trichoplein, keratin filament binding L homeolog antikoerper, TCHP antikoerper, tchp antikoerper, Tchp antikoerper, tchp.L antikoerper
    Hintergrund

    Background: Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a \'capping\' or \'branching\' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis (PubMed:25270598).

    Aliases: TCHP antibody, Trichoplein keratin filament-binding protein antibody, Protein TCHP antibody, Mitochondrial protein with oncostatic activity antibody, Mitostatin antibody, Tumor suppressor protein antibody

    UniProt
    Q9BT92
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