TCHP Antikörper (AA 1-498) (Biotin)
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- Target Alle TCHP Antikörper anzeigen
- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
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Bindungsspezifität
- AA 1-498
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TCHP Antikörper ist konjugiert mit Biotin
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Applikation
- ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Trichoplein keratin filament-binding protein (1-498AA)
- Isotyp
- IgG
- Top Product
- Discover our top product TCHP Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
- Andere Bezeichnung
- TCHP (TCHP Produkte)
- Synonyme
- TpMs antikoerper, A930031F18Rik antikoerper, AV279199 antikoerper, RGD1310813 antikoerper, zgc:136634 antikoerper, trichoplein keratin filament binding antikoerper, trichoplein, keratin filament binding antikoerper, trichoplein, keratin filament binding L homeolog antikoerper, TCHP antikoerper, tchp antikoerper, Tchp antikoerper, tchp.L antikoerper
- Hintergrund
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Background: Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a \'capping\' or \'branching\' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis (PubMed:25270598).
Aliases: TCHP antibody, Trichoplein keratin filament-binding protein antibody, Protein TCHP antibody, Mitochondrial protein with oncostatic activity antibody, Mitostatin antibody, Tumor suppressor protein antibody
- UniProt
- Q9BT92
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