TSC22D3 Antikörper (AA 58-134)

Produktnummer ABIN7173626

Produktdetails anti-TSC22D3 Antikörper

Target: TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))

Bindungsspezifität: AA 58-134

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSC22D3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human TSC22 domain family protein 3 protein (58-134AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TSC22D3

Target: TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))

Andere Bezeichnung: TSC22D3 (TSC22D3 Produkte)

Synonyme: dsipi antikoerper, MGC53285 antikoerper, zgc:65831 antikoerper, zgc:77028 antikoerper, TSC22D3 antikoerper, GILZ antikoerper, gilz antikoerper, tsc-22r antikoerper, DIP antikoerper, DSIPI antikoerper, TSC-22R antikoerper, hDIP antikoerper, Dsip1 antikoerper, Gilz antikoerper, Tilz3 antikoerper, Dsipi antikoerper, DSIP antikoerper, TSC22 domain family member 3 L homeolog antikoerper, TSC22 domain family, member 3 antikoerper, TSC22 domain family member 3 antikoerper, tsc22d3.L antikoerper, tsc22d3 antikoerper, TSC22D3 antikoerper, Tsc22d3 antikoerper

Hintergrund:

Background: Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Isoform 1 inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG.

Aliases: Delta sleep-inducing peptide immunoreactor antibody, DIP antibody, DSIP immunoreactive leucine zipper protein antibody, DSIP-immunoreactive peptide antibody, Dsip1 antibody, Dsipi antibody, GILZ antibody, Glucocorticoid-induced leucine zipper protein antibody, hDIP antibody, Protein DIP antibody, T22D3_HUMAN antibody, TSC-22-like protein antibody, TSC-22-related protein antibody, TSC-22R antibody, TSC22 domain family protein 3 antibody, TSC22 domain family, member 3 antibody, TSC22 related inducible leucine zipper 3 antibody, TSC22D3 antibody

UniProt: Q99576