TRADD Antikörper (AA 1-312)

Produktnummer ABIN7173904

Produktdetails anti-TRADD Antikörper

Target: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Bindungsspezifität: AA 1-312

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRADD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Kreuzreaktivität: Human, Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Tumor necrosis factor receptor type 1-associated DEATH domain protein (1-312AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200, IP:1:200-1:2000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TRADD

Target: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Andere Bezeichnung: TRADD (TRADD Produkte)

Synonyme: TRADD antikoerper, Hs.89862 antikoerper, 9130005N23Rik antikoerper, AA930854 antikoerper, wu:fc59e02 antikoerper, zgc:103556 antikoerper, tradd antikoerper, TNFRSF1A associated via death domain antikoerper, conjugal transfer protein D antikoerper, TNFRSF1A-associated via death domain antikoerper, TNFRSF1A-associated via death domain L homeolog antikoerper, tnfrsf1a-associated via death domain antikoerper, TRADD antikoerper, traDd antikoerper, Tradd antikoerper, tradd.L antikoerper, tradd antikoerper

Hintergrund:

Background: The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.

Aliases: 9130005N23Rik antibody, AA930854 antibody, TNFR1 associated DEATH domain protein antibody, TNFR1-associated DEATH domain protein antibody, TNFRSF1A associated via death domain antibody, TNFRSF1A-associated via death domain antibody, tradd antibody, TRADD_HUMAN antibody, Tumor necrosis factor receptor type 1 associated DEATH domain protein antibody, Tumor necrosis factor receptor type 1-associated DEATH domain protein antibody

UniProt: Q15628

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Hepatitis C