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USP33 Antikörper (C-Term) (Biotin)

USP33 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN7174317
  • Target Alle USP33 Antikörper anzeigen
    USP33 (Ubiquitin Specific Peptidase 33 (USP33))
    Bindungsspezifität
    • 15
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 251-550, C-Term
    Reaktivität
    • 38
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 36
    • 2
    Kaninchen
    Klonalität
    • 36
    • 2
    Polyklonal
    Konjugat
    • 21
    • 4
    • 4
    • 3
    • 3
    • 3
    Dieser USP33 Antikörper ist konjugiert mit Biotin
    Applikation
    • 23
    • 21
    • 20
    • 9
    • 6
    • 6
    • 2
    • 1
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 33 protein (251-550AA)
    Isotyp
    IgG
    Top Product
    Discover our top product USP33 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    USP33 (Ubiquitin Specific Peptidase 33 (USP33))
    Andere Bezeichnung
    USP33 (USP33 Produkte)
    Synonyme
    USP33 antikoerper, VDU1 antikoerper, 9830169D19Rik antikoerper, AA409780 antikoerper, Vdu1 antikoerper, zgc:77308 antikoerper, ubiquitin specific peptidase 33 antikoerper, universal stress protein UspA antikoerper, Usp33 antikoerper, USP33 antikoerper, RR_RS17870 antikoerper, usp33 antikoerper
    Hintergrund

    Background: Deubiquitinating enzyme involved in various processes such as centrosome duplication, cellular migration and beta-2 adrenergic receptor/ADRB2 recycling. Involved in regulation of centrosome duplication by mediating deubiquitination of CCP110 in S and G2/M phase, leading to stabilize CCP110 during the period which centrioles duplicate and elongate. Involved in cell migration via its interaction with intracellular domain of ROBO1, leading to regulate the Slit signaling. Plays a role in commissural axon guidance cross the ventral midline of the neural tube in a Slit-dependent manner, possibly by mediating the deubiquitination of ROBO1. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination of beta-arrestins (ARRB1 and ARRB2) and beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Mediates deubiquitination of both \'Lys-48\'- and \'Lys-63\'-linked polyubiquitin chains.

    Aliases: Deubiquitinating enzyme 33 antibody, EC 3 1 2 15 antibody, hVDU1 antibody, KIAA1097 antibody, MGC16868 antibody, OTTHUMP00000011234 antibody, OTTHUMP00000011330 antibody, OTTHUMP00000011331 antibody, pVHL interacting deubiquitinating enzyme 1 antibody, Ubiquitin carboxyl terminal hydrolase 33 antibody, Ubiquitin carboxyl-terminal hydrolase 33 antibody, Ubiquitin specific peptidase 33 antibody, Ubiquitin specific processing protease 33 antibody, ubiquitin specific protease 33 antibody, Ubiquitin thioesterase 33 antibody, Ubiquitin thiolesterase 33 antibody, Ubiquitin-specific-processing protease 33 antibody, UBP33_HUMAN antibody, USP 33 antibody, Usp33 antibody, VDU 1 antibody, VDU1 antibody, VHL interacting deubiquitinating enzyme 1 antibody, VHL-interacting deubiquitinating enzyme 1 antibody

    UniProt
    Q8TEY7
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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