UFD1L Antikörper (AA 1-307)
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- Target Alle UFD1L Antikörper anzeigen
- UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
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Bindungsspezifität
- AA 1-307
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser UFD1L Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Ubiquitin recognition factor in ER-associated degradation protein 1 protein (1-307AA)
- Isotyp
- IgG
- Top Product
- Discover our top product UFD1L Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
- Andere Bezeichnung
- UFD1 (UFD1L Produkte)
- Hintergrund
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Background: Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures.
Aliases: UB fusion protein 1 antibody, Ubiquitin fusion degradation 1 like (yeast) antibody, Ubiquitin fusion degradation 1 like antibody, Ubiquitin fusion degradation protein 1 homolog antibody, UFD1 antibody, UFD1_HUMAN antibody, UFD1L antibody
- UniProt
- Q92890
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