UFM1 Antikörper (AA 11-63)

Produktnummer ABIN7174508

Produktdetails anti-UFM1 Antikörper

Target: UFM1 (Ubiquitin-Fold Modifier 1 (UFM1))

Bindungsspezifität: AA 11-63

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UFM1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin-fold modifier 1 protein (11-63AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu UFM1

Target: UFM1 (Ubiquitin-Fold Modifier 1 (UFM1))

Andere Bezeichnung: UFM1 (UFM1 Produkte)

Synonyme: T32E8.4 antikoerper, T32E8_4 antikoerper, BM-002 antikoerper, C13orf20 antikoerper, bA131P10.1 antikoerper, 1810045K17Rik antikoerper, AI132708 antikoerper, AI463323 antikoerper, ENSMUSG00000074598 antikoerper, Gm10726 antikoerper, RGD1304890 antikoerper, UBFM1 antikoerper, ubfm1 antikoerper, wu:fa10f05 antikoerper, wu:fb72g01 antikoerper, zgc:55335 antikoerper, ubiquitin fold modifier 1 antikoerper, ubiquitin-fold modifier 1 antikoerper, ubiquitin-fold modifier antikoerper, ubiquitin-fold modifier 1 L homeolog antikoerper, UFM1 antikoerper, ufm1 antikoerper, CCP2 antikoerper, Ufm1 antikoerper, ufm1.L antikoerper, PR46a antikoerper

Hintergrund:

Background: Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer. The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 (PubMed:15071506, PubMed:20018847). This post-translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes. TRIP4 ufmylation may for instance play a role in nuclear receptors-mediated transcription (PubMed:25219498). Other substrates may include DDRGK1 with which it may play a role in the cellular response to endoplasmic reticulum stress (Probable).

Aliases: BM 002 antibody, BM002 antibody, C13orf20 antibody, Chromosome 13 open reading frame 20 antibody, Ubiquitin fold modifier 1 antibody, Ubiquitin-fold modifier 1 antibody, UFM1 antibody, UFM1_HUMAN antibody

UniProt: P61960