UGT1A1 Antikörper (AA 395-482)

Produktnummer ABIN7174623

Produktdetails anti-UGT1A1 Antikörper

Target: UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))

Bindungsspezifität: AA 395-482

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UGT1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human UDP-glucuronosyltransferase 1-1 protein (395-482AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu UGT1A1

Target: UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))

Andere Bezeichnung: UGT1A1 (UGT1A1 Produkte)

Synonyme: BILIQTL1 antikoerper, GNT1 antikoerper, HUG-BR1 antikoerper, UDPGT antikoerper, UDPGT 1-1 antikoerper, UGT1 antikoerper, UGT1A antikoerper, Gnt1 antikoerper, UGT1A01 antikoerper, Udpgt-1a antikoerper, UgtBr1 antikoerper, Udpgt antikoerper, Ugt1 antikoerper, zgc:123097 antikoerper, UDP glucuronosyltransferase family 1 member A1 antikoerper, UDP glucuronosyltransferase 1 family, polypeptide A1 antikoerper, UDP-glucuronosyltransferase 1-1 antikoerper, UDP-glucuronosyltransferase antikoerper, UDP-glucuronosyltransferase 1-6 antikoerper, UDP glucuronosyltransferase 1 family polypeptide a1 antikoerper, UGT1A1 antikoerper, Ugt1a1 antikoerper, LOC100065342 antikoerper, LOC100125517 antikoerper, LOC100229734 antikoerper, LOC100405984 antikoerper, LOC100511479 antikoerper, ugt1a1 antikoerper

Hintergrund:

Background: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Is also able to catalyze the glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1.

Aliases: BILIQTL1 antibody, Bilirubin specific UDPGT isozyme 1 antibody, bilirubin UDP glucuronosyltransferase 1 1 antibody, bilirubin UDP glucuronosyltransferase isozyme 1 antibody, Bilirubin-specific UDPGT isozyme 1 antibody, EC 2.4.1.17 antibody, GNT1 antibody, HUG BR1 antibody, HUG-BR1 antibody, HUGBR1 antibody, PHENOL/BILIRUBIN UDP GLUCURONOSYLTRANSFERASE antibody, UD11_HUMAN antibody, UDP glucuronosyltransferase 1 1 [Precursor] antibody, UDP glucuronosyltransferase 1 family polypeptide A1 antibody, UDP glucuronosyltransferase 1A1 antibody, UDP GLYCOSYLTRANSFERASE 1 antibody, UDP-glucuronosyltransferase 1-1 antibody, UDP-glucuronosyltransferase 1-A antibody, UDP-glucuronosyltransferase 1A1 antibody, UDPGT antibody, UDPGT 1-1 antibody, UGT 1A antibody, UGT-1A antibody, UGT1 antibody, UGT1 01 antibody, UGT1*1 antibody, UGT1-01 antibody, UGT1.1 antibody, UGT1A antibody, Ugt1a1 antibody, URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE, BILIRUBIN/PHENOL antibody, URIDINE DIPHOSPHATE GLYCOSYLTRANSFERASE 1 antibody, URIDINE DIPHOSPHATE GLYCOSYLTRANSFERASE 1 FAMILY, POLYPEPTIDE A1 antibody

UniProt: P22309

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha