UVSSA/KIAA1530 Antikörper (AA 143-206) (FITC)
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- Target Alle UVSSA/KIAA1530 (UVSSA) Antikörper anzeigen
- UVSSA/KIAA1530 (UVSSA) (UV Stimulated Scaffold Protein A (UVSSA))
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Bindungsspezifität
- AA 143-206
- Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser UVSSA/KIAA1530 Antikörper ist konjugiert mit FITC
- Applikation
- Bitte anfragen
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human UV-stimulated scaffold protein A protein (143-206AA)
- Isotyp
- IgG
- Top Product
- Discover our top product UVSSA Primärantikörper
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- UVSSA/KIAA1530 (UVSSA) (UV Stimulated Scaffold Protein A (UVSSA))
- Andere Bezeichnung
- UVSSA (UVSSA Produkte)
- Synonyme
- KIAA1530 antikoerper, UVSS3 antikoerper, kiaa1530 antikoerper, 4933407H18Rik antikoerper, D330017J19Rik antikoerper, Kiaa1530 antikoerper, mKIAA1530 antikoerper, UV stimulated scaffold protein A antikoerper, UVSSA antikoerper, uvssa antikoerper, Uvssa antikoerper
- Hintergrund
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Background: Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced degradation of ERCC6 by the proteasome. Interacts with the elongating form of RNA polymerase II (RNA pol IIo) and facilitates its ubiquitination at UV damage sites, leading to promote RNA pol IIo backtracking to allow access to the nucleotide excision repair machinery. Not involved in processing oxidative damage.
Aliases: hypothetical protein LOC57654 antibody, K1530_HUMAN antibody, KIAA1530 antibody, Uncharacterized protein KIAA1530 antibody, UV stimulated scaffold protein A antibody, UVSS3 antibody, UVSSA antibody
- UniProt
- Q2YD98
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