SNF8 Antikörper (AA 1-258)
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- Target Alle SNF8 Antikörper anzeigen
- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
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Bindungsspezifität
- AA 1-258
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SNF8 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Vacuolar-sorting protein SNF8 protein (1-258AA)
- Isotyp
- IgG
- Top Product
- Discover our top product SNF8 Primärantikörper
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- Applikationshinweise
- Recommended dilution: IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
- Andere Bezeichnung
- SNF8 (SNF8 Produkte)
- Hintergrund
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Background: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. Required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is also required for the degradation of CXCR4. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).
Aliases: Dot3 antibody, ELL associated protein of 30 kDa antibody, ELL-associated protein of 30 kDa antibody, ESCRT-II complex subunit VPS22 antibody, hVps22 antibody, snf8 antibody, SNF8 ESCRTII complex subunit homolog (S cerevisiae) antibody, SNF8_HUMAN antibody, Vacuolar sorting protein SNF8 antibody, Vacuolar-sorting protein SNF8 antibody, VPS22 antibody
- UniProt
- Q96H20
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