WDR41 Antikörper (AA 7-284) (FITC)
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- Target Alle WDR41 Produkte
- WDR41 (WD Repeat Domain 41 (WDR41))
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Bindungsspezifität
- AA 7-284
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser WDR41 Antikörper ist konjugiert mit FITC
- Applikation
- Bitte anfragen
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human WD repeat-containing protein 41 protein (7-284AA)
- Isotyp
- IgG
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- WDR41 (WD Repeat Domain 41 (WDR41))
- Andere Bezeichnung
- WDR41 (WDR41 Produkte)
- Synonyme
- WDR41 antikoerper, MGC142930 antikoerper, wdr41 antikoerper, fj48d04 antikoerper, wu:fj48d04 antikoerper, zgc:110041 antikoerper, B830029I03Rik antikoerper, MSTP048 antikoerper, WD repeat domain 41 antikoerper, Wdr41 antikoerper, WDR41 antikoerper, wdr41 antikoerper
- Hintergrund
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Background: Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy (PubMed:27193190, PubMed:27103069, PubMed:27617292, PubMed:28195531). The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation (PubMed:27103069). The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity (PubMed:27103069, PubMed:27617292).
Aliases: FLJ10904 antibody, MSTP048 antibody, WD repeat domain 41 antibody, WD repeat protein 41 antibody, WD repeat-containing protein 41 antibody, WDR 41 antibody, WDR41 antibody, WDR41_HUMAN antibody
- UniProt
- Q9HAD4
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