GLIS2 Antikörper (AA 332-505)

Produktnummer ABIN7176582

Der Kaninchen Polyklonal Anti-GLIS2-Antikörper wurde für ELISA, IHC und IF validiert. Er ist geeignet, GLIS2 in Proben von Human zu detektieren.

Kurzübersicht für GLIS2 Antikörper (AA 332-505) (ABIN7176582)

Target: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLIS2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-GLIS2 Antikörper

Bindungsspezifität: AA 332-505

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Zinc finger protein GLIS2 protein (332-505AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GLIS2

Target: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Andere Bezeichnung: GLIS2

Hintergrund:

Background: Can act either as a transcriptional repressor or as a transcriptional activator, depending on the cell context. Acts as a repressor of the Hedgehog signaling pathway (By similarity). Represses the Hedgehog-dependent expression of Wnt4 (By similarity). Necessary to maintain the differentiated epithelial phenotype in renal cells through the inhibition of SNAI1, which itself induces the epithelial-to-mesenchymal transition (By similarity). Represses transcriptional activation mediated by CTNNB1 in the Wnt signaling pathway. May act by recruiting the corepressors CTBP1 and HDAC3. May be involved in neuron differentiation (By similarity).

Aliases: FLJ38247 antibody, GLI similar 2 antibody, GLI-similar 2 antibody, GLIS 2 antibody, GLIS family zinc finger 2 antibody, glis2 antibody, GLIS2_HUMAN antibody, Kruppel like zinc finger protein GLIS2 antibody, Neuronal Krueppel-like protein antibody, Zinc finger protein GLIS2 antibody

UniProt: Q9BZE0