SAMHD1 Antikörper (AA 426-657)

Produktnummer ABIN7177149

Produktdetails anti-SAMHD1 Antikörper

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Bindungsspezifität: AA 426-657

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAMHD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Mouse Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 protein (426-657AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SAMHD1

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Andere Bezeichnung: Samhd1 (SAMHD1 Produkte)

Hintergrund:

Background: Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling (By similarity).

Aliases: Samhd1 antibody, Mg21 antibody, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 antibody, dNTPase antibody, EC 3.1.5.- antibody, Interferon-gamma-inducible protein Mg11 antibody, SAM domain and HD domain-containing protein 1 antibody, mSAMHD1 antibody

UniProt: Q60710