HSPA1B Antikörper (AA 2-642) (Biotin)

Produktnummer ABIN7177278

Produktdetails anti-HSPA1B Antikörper (Biotin)

Target: HSPA1B (Heat Shock 70kDa Protein 1B (HSPA1B))

Bindungsspezifität: AA 2-642

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSPA1B Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Mouse Heat shock 70 kDa protein 1B protein (2-642AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HSPA1B

Target: HSPA1B (Heat Shock 70kDa Protein 1B (HSPA1B))

Andere Bezeichnung: Hspa1b (HSPA1B Produkte)

Hintergrund:

Background: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Essential for STUB1-mediated ubiquitination and degradation of FOXP3 in regulatory T-cells (Treg) during inflammation.

Aliases: Hspa1b antibody, Hcp70.1 antibody, Hsp70-1 antibody, Hsp70a1 antibody, Hspa1 antibody, Heat shock 70 kDa protein 1B antibody, Heat shock 70 kDa protein 1 antibody, HSP70.1 antibody

UniProt: P17879